CD54 / ICAM-1 (F4-31C2), CF647 conjugate, 0.1mg/mL
CD54 / ICAM-1 (F4-31C2), CF647 conjugate, 0.1mg/mL thumbnail 1
GTR00905451

CD54 / ICAM-1 (F4-31C2), CF647 conjugate, 0.1mg/mL

ml-0-conjugate

$645.08($853.12)
Size: 1x 500 µL

Description

Recognizes an 85-115 kDa protein (variation with cell type), identified as intercellular adhesion molecule (ICAM-1) . It has 7 potential N-linked glycosylation sites. ICAM-1 is a single chain glycoprotein of Ig supergene family, present on unstimulated endothelial cells (EC) and on a variety of other cell types including activated fibroblasts, EC, macrophages, and lymphocytes. ICAM-1 mediates cell adhesion by binding to integrins CD11a/CD18 (leukocyte adhesion molecule, LFA-1) and to CD11b/CD18 (Mac-1) . This interaction enhances antigen-specific T-cell activation. ICAM-1 also binds to CD43 and to Plasmodium falciparum infected RBCs. ICAM-1 may also be related to progression and metastasis of tumors.

Specifications

CAS Number
9007-83-4
Synonyms
CD54; Cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM-1; Intercellular adhesion molecule 1; Ly 47; Major group rhinovirus receptor; MALA2; MyD10; Surface antigen of activated B cells
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Source
Animal
Host
Mouse
Shipping
RT (ND)
Storage
Stable at room temperature or 37°C (98°F) for 7 days.

Variants

1x 500 µL (BNC471249-500)$645.08

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